The following instructions will set up pipedec to use FFmpeg to encode using the lossless FFV1 codec as an example, but pipedec can be configured to pipe video to any encoder you want. In cases where avoiding these splits is desirable (for instance, emulators that don't handle the split well and desync the audio/video), or where using a more modern codec (like lossless h.264) is preferable to VFW codecs, pipedec can be used.
Many of the emulators listed here dump video via VFW codecs, and must split those videos at 2GB intervals due to limitations in the aging technology.
Non-VFW Codecs via pipedec (Windows only).